The use of blood products has been for a long time in history. PRP definition is a rich concentration of platelets in a small volume of plasma from the patient’s own blood-Autologous.
It is not a concoction like mesotherapy and hair laser which have no science. The extensive use of PRP in dermatology, dentistry , orthopedics, ophthalmology and even cardiology shows there is a certain science.
Platelets have 20 growth factors that cause angiogenesis – New skin vessel formation, Collagenogenesis – new collagen deposit and increased fibroblasts which all lead to skin rejuvenation and scar attenuation.
The effect of PRP in reducing wrinkles was assessed using wrinkle severity rating study in 20 patients. A significant reduction in wrinkles was seen along with improvement in skin tightening and clearer skin with increased volume of skin. Response was reduced in patients over 40.
PRP is also combined with PDO( Polydioxanone) threads to treat Androgenic alopecia or male or female patterned hair loss.
Intra Follicular PRP injections when combined with PDO threads form a bio scaffolding or an envelope that keeps the growth factors activated and released for at least nine months by mechanotransduction. This increases the interval time between two PRP sessions by at least nine months and increased patient acceptability to PRP treatments for hair loss.
With inputs from dermatologist Dr Satish Bhatia MD,FAAD.